Cognitive-motor telerehabilitation in multiple sclerosis: CoMoTeMS study
What? 12-week telerehabilitation program
Who? Persons with MS between 18 and 65, with an EDSS score of less than 6.0 (i.e. who can walk minimum 100 meters without aid)
Where? 4 testing sessions in UZ Brussel/VUB Jette
When? Start in September 2022
The management of cognitive impairment is an important goal in the treatment of multiple sclerosis (MS). While cognitive rehabilitation has been proven to be effective in improving cognitive performance in MS, research in the elderly indicates a higher effectiveness of combined cognitive-motor rehabilitation.
In the CoMoTeMS-trial 90 patients with MS will receive 12 weeks of either a combined cognitive-motor telerehabilitation program or only cognitive or motor training. The primary outcome is a change in the digit span backwards, a test of working memory. Secondary outcomes are other cognitive changes (Brief International Cognitive Assessment for Multiple Sclerosis and Backward Corsi), Expanded Disability Status Scale (EDSS), 6-Minute Walk Test, 25-Foot Walk Test, 9-Hole Peg Test, anxiety and depression, fatigue, quality of life, cognitive and physical activity level, electroencephalography and magnetic resonance imaging of the brain.
We will assess:
- The effectiveness of the three training programs
- The mechanisms of improvement
- The predictors of treatment response
Questions? Do not hesitate to contact Delphine.Van.Laethem@vub.be.