In this project we are investigating the relationship between cerebral blood flow and MS. To measure blood flow, we are using an MRI technique called “Arterial Spin Labeling.” Alongside this, we’ll conduct cognitive assessments and standard MRI scans (T1 and FLAIR) to evaluate neurocognitive functioning and structural brain changes.
After about two years, the MS patients will return for a follow-up study with the same evaluations. This long-term approach will help us understand how changes in blood flow correlate with the progression of MS and whether initial blood flow measurements can serve as predictive markers for structural brain changes and/or cognitive shifts.
Additionally, we will assess the effect of transcranial direct current stimulation (tDCS) on cerebral blood flow. We will measure blood flow before, during, and after tDCS to examine how it affects cerebral blood flow in both healthy controls and MS patients
